Corticosteroid Knee Injection

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Corticosteroid Knee Injection

Corticosteroid Injection Key Points

Composition : The injectable formulation is commonly methylprednisolone or triamcinolone.

Corticosteroids are typically combined with local anesthetic such as lidocaine or bupivacaine

Mechanism of action:   Corticosteroids reduce inflammation by altering B- and T-cell function as well as stimulating HA synthesis.

Efficacy: Synovitis, effusion, or mild OA may predict the therapeutic benefit.
AAOS has stated that there is inconclusive evidence to recommend for or against the use of intra-articular corticosteroids to treat knee OA.

Complications: In 3%-25% of patients, a flare may occur in the days after an injection, but this does not interfere with the therapeutic benefit.AAOS, American Academy of Orthopaedic Surgeons; HA, hyaluronic acid; OA, osteoarthritis. More Info

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